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Tarja Porkka-Heiskanen Selected Research

Sleep Deprivation

10/2018Intracerebral Adenosine During Sleep Deprivation: A Meta-Analysis and New Experimental Data.
1/2017Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia.
1/2016Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.
4/2015Spontaneous sleep-wake cycle and sleep deprivation differently induce Bdnf1, Bdnf4 and Bdnf9a DNA methylation and transcripts levels in the basal forebrain and frontal cortex in rats.
1/2013Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans.
9/2012Histamine release in the basal forebrain mediates cortical activation through cholinergic neurons.
10/2011Automated sleep scoring in rats and mice using the naive Bayes classifier.
1/2011Methylxanthines and sleep.
1/2011The time course of adenosine, nitric oxide (NO) and inducible NO synthase changes in the brain with sleep loss and their role in the non-rapid eye movement sleep homeostatic cascade.
11/2010Nitric oxide mediated recovery sleep is attenuated with aging.
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Tarja Porkka-Heiskanen Research Topics

Disease

20Sleep Deprivation
10/2018 - 02/2003
2Fatigue
01/2011 - 03/2010
1Schizophrenia (Dementia Praecox)
01/2017
1Bipolar Disorder (Manic Depressive Psychosis)
01/2017
1Hyperammonemia
01/2017
1Sleepiness
01/2017
1Sleep Initiation and Maintenance Disorders (Insomnia)
05/2016
1Mood Disorders (Mood Disorder)
10/2011
1Type 2 Diabetes Mellitus (MODY)
01/2010
1Cardiovascular Diseases (Cardiovascular Disease)
01/2009
1Mental Disorders (Mental Disorder)
06/2006
1Antisocial Personality Disorder (Antisocial Personality)
07/2005
1Asperger Syndrome (Asperger's Syndrome)
06/2005
1Psychomotor Agitation (Akathisia)
08/2004
1Weight Gain
01/2003
1Anorexia Nervosa
01/2003
1Starvation
01/2003
1Malnutrition (Nutritional Deficiencies)
01/2003
1Hypoxia (Hypoxemia)
08/2002
1Ischemia
08/2002

Drug/Important Bio-Agent (IBA)

10Adenosine (Adenocard)FDA LinkGeneric
10/2018 - 08/2002
3Lactic Acid (Lactate)FDA LinkGeneric
09/2009 - 02/2003
2Glucose (Dextrose)FDA LinkGeneric
05/2016 - 01/2010
2Brain-Derived Neurotrophic Factor (BDNF)IBA
04/2015 - 03/2010
2Pharmaceutical PreparationsIBA
10/2011 - 07/2005
2Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2011 - 11/2010
2Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2010 - 10/2010
2Insulin-Like Growth Factor I (IGF-1)IBA
01/2010 - 01/2003
2Insulin (Novolin)FDA Link
01/2010 - 01/2003
1Dialysis SolutionsIBA
10/2018
1Adenosine Monophosphate (AMP)IBA
10/2018
1CalciumIBA
01/2017
1Ammonium CompoundsIBA
01/2017
1AmmoniaIBA
01/2017
1oxidized low density lipoproteinIBA
01/2016
1Lipoproteins (Lipoprotein)IBA
01/2016
1CholesterolIBA
01/2016
1DNA (Deoxyribonucleic Acid)IBA
04/2015
15-Methylcytosine (5 Methylcytosine)IBA
04/2015
1betaglycan (TGFBR3)IBA
01/2013
1Histamine (Histamine Dihydrochloride)FDA Link
09/2012
1Biological ProductsIBA
10/2011
1Caffeine (No Doz)FDA LinkGeneric
01/2011
1Cholinergic Agents (Cholinergics)IBA
11/2010
1Coloring Agents (Dyes)IBA
10/2010
1Interleukin-17 (Interleukin 17)IBA
01/2009
1Interleukin-6 (Interleukin 6)IBA
01/2009
1CytokinesIBA
01/2009
1Protons (Proton)IBA
06/2006
1Adrenocorticotropic Hormone (ACTH)FDA Link
06/2005
1Hydrocortisone (Cortisol)FDA LinkGeneric
06/2005
1GTP-Binding Proteins (G-Protein)IBA
09/2004
1Antipsychotic Agents (Antipsychotics)IBA
08/2004
1OrexinsIBA
02/2004
14-nitrobenzylthioinosineIBA
12/2003
1Pyruvic Acid (Pyruvate)IBA
02/2003
1Appetite Depressants (Anorectics)IBA
01/2003
1Growth Hormone (Somatotropin)IBA
01/2003
1LeptinIBA
01/2003